COVID-19 vaccination refers to the ongoing global effort to develop and distribute vaccines to protect against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the coronavirus disease 2019 (COVID-19). The vaccines work by training the immune system to recognize and fight the virus, thereby reducing the severity of illness and preventing transmission. Various vaccines have been developed and authorized for emergency use around the world, with vaccination campaigns being implemented to immunize populations and control the spread of the virus. Efforts are ongoing to ensure equitable access to vaccines, address vaccine hesitancy, monitor vaccine effectiveness, and adapt to emerging variants of the virus.